Ian Wark Research Institute
ARC Special Research Centre
ARC Special Research Centre
Research Area: physical chemistry, pharmaceutical science
Supervisors:
A/Prof David Beattie and
Dr Kristen Bremmell (School of Pharmacy and Medical Sciences)
Description: The storage and release of small therapeutic
molecules from surfaces and colloidal systems is a key goal of many drug
delivery studies. Polymer multilayer films represent a very attractive
class of surface treatments that can be used for this purpose. Such
films can be made to be biocompatible, non-fouling, and lubricious. In
addition, these layers can be produced in such a way as to make them
stimulus responsive, i.e. their composition and properties can be
altered by ‘flicking a switch’ in the system, such as changing
temperature, pH, or exposure to UV light.
The aim of this project is to use such films to selectively absorb and release model therapeutic agents in response to such stimuli.
