Dr Bryan Coad
Contact Details
Tel: +61 8 8302 3152
Fax: +61 8 8302 3683
Email:
bryan.coad@unisa.edu.au
Position
Research Fellow (joint Wark/Mawson Institute)
Qualifications
BSc Simon Fraser, Canada PhD British Columbia, Canada
Background
Bryan Coad completed his Bachelor of Science degree from Simon Fraser
University in Vancouver Canada in 1997. He worked in research and
development at Canadian Inovatech Inc chromatograhically purifying proteins
from agricultural sources until 2000. In 2001 he commenced his PhD at the
University of British Columbia in Vancouver, Canada. Through the department
of Chemistry and funded by the Centre for Blood Research, Bryan defended his
thesis in 2006 describing the synthesis and evaluation of an entropically
driven chromatography mode for separation of blood plasma proteins.
After moving to Melbourne, Bryan completed two postdoctoral research
appointments at Monash University and then CSIRO funded by the CRC for
Polymers Biomanufacturing Project to address new polymer technologies for
controlling cell function. The subject of Bryan's postdoctoral research has
largely been focussed towards commercial outcomes with research contributing
towards many proprietary advancements including one co-authored invention.
Bryan joined UniSA in 2010 where he currently holds a joint Research Fellow
appointment with the Ian Wark Research Institute and the Mawson Institute
with Professor Hans Griesser and Professor Rob Short. Bryan's current
research project sees him contributing to understanding the biological /
material interface with research geared towards the application of plasma
polymerisation technology towards cell diagnostics and tissue engineering.
Research Interests
Chemistry of the biological / material interface
Plasma polymerisation
Smart materials
Polymer brushes
New materials for chromatography
Patents
Tsang, K.; Hou, X.; Coad, B.; Forsythe, J. S.; Meagher, L.; Thissen, H. W.;
Ameringer, T.; Evans, R. A.; Pasic, P. Electrospun polymer fiber useful for
manufacture of polymer brushes that are useful in textile manufacturing to
prepare scaffolds for cell culture, comprises living polymerization moieties
that are covalently bound to its polymer surface. WO 2010/020008 A1, 2010.
Publications
Coad, B. R.; Lu, Y.; Glattauer, V.; Meagher, L., A Substrate Independent
Method for Growing and Modulating the Density of Polymer Brushes from
Surfaces by ATRP. ACS Applied Materials & Interfaces 2012. DOI
10.1021/am300128n
Coad, B. R.; Scholz, T.; Vasilev, K.; Hayball, J. D.; Short, R. D.;
Griesser, H. J., Functionality of proteins bound to plasma polymer surfaces.
ACS Applied Materials & Interfaces 2012. DOI 10.1021/am300463q
Coad, B. R.; Vasilev, K.; Diener, K. R.; Hayball, J. D.; Short, R. D.;
Griesser, H. J., Immobilized Streptavidin Gradients as Bioconjugation
Platforms. Langmuir 2012, 28, (5), 2710-2717.
Christo, S. N.; Sarvestani, G. T.; Griesser, S. S.; Coad, B. R.; Griesser,
H. J.; Vasilev, K.; Brown, M. P.; Diener, K. R.; Hayball, J. D., Individual
and Population Quantitative Analyses of Calcium Flux in T-Cells Activated on
Functionalized Material Surfaces. Aust. J. Chem. 2012, 65, 45-49.
Coad, B. R.; Lu, Y.; Meagher, L., A Substrate-Independent Method for
Surface Grafting Polymer Layers by Atom Transfer Radical Polymerization:
Reduction of Protein Adsorption. Acta Biomater. 2012, 8, 608-618.
Coad, B. R.; Kizhakkedathu, J. N.; Haynes, C. A.; Brooks, D. E., Synthesis
of Novel Size Exclusion Chromatography Support by Surface Initiated Aqueous
Atom Transfer Radical Polymerization. Langmuir 2007, 23, (23), 11791-11803.
Coad, B. R.; Steels, B. M.; Kizhakkedathu, J. N.; Brooks, D. E.; Haynes, C.
A., The Influence of Grafted Polymer Architecture and Fluid Hydrodynamics on
Protein Separation by Entropic Interaction Chromatography. Biotechnology and
Bioengineering 2006, 97, (3), 574-587.
Pang, P.; Koska, J.; Coad, B. R.; Brooks, D. E.; Haynes, C. A., Entropic
interaction chromatography: Separating proteins on the basis of size using
end-grafted polymer brushes. Biotechnology and Bioengineering 2005, 90, (1),
1-13.